We present a recently developed approach for the modeling of fluid-solid-acoustic interaction problems. For the efficient numerical solution of the coupled three-field problem we apply the finite-element method. The mechanical and the acoustic fields are approximated by a standard Galerkin scheme. A residual-based stabilization method is chosen for the fluid field. The interaction of the Eulerian fluid field with the Lagrangian mechanical field is based on the Arbitrary-Lagrangian-Eulerian (ALE) method and is iteratively coupled in a strong sense. The solid-acoustic interaction is based on continuum mechanics, and the fluid-acoustic coupling on Lighthill's analogy. The new steps of our scheme are verified through validation examples. Finally, a fluid-solid-acoustic simulation of the human phonation process is presented based on a realistic model. © 2009 Elsevier B.V. All rights reserved.