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  5. Deep learning-based detection of tuberculosis using a Gaussian chest X-Ray image filter as a software lens

Deep learning-based detection of tuberculosis using a Gaussian chest X-Ray image filter as a software lens

Publication date
2025-02
Document type
Forschungsartikel
Author
Eisentraut, Luca  
Mai, Christopher  
Hosch, Johanna
Benecke, Amélie
Penava, Pascal  
Buettner, Ricardo  
Organisational unit
Hybrid Intelligence  
DOI
10.1109/access.2025.3544923
URI
https://openhsu.ub.hsu-hh.de/handle/10.24405/22996
Publisher
IEEE
Series or journal
IEEE Access
ISSN
2169-3536
Periodical volume
13
First page
36065
Last page
36081
Peer-reviewed
✅
Part of the university bibliography
✅
Additional Information
Language
English
Abstract
Tuberculosis remains one of the most prevalent and lethal infectious diseases, with millions of cases reported each year. Convolutional neural networks have proven effective in detecting such diseases from medical images, achieving high accuracy in identifying tuberculosis from chest X-rays. However, many models are limited by small datasets, lack of cross-validation or have not achieved an optimal level of detection performance. In the context of diagnosing diseases, it is crucial to continually strive for increasingly accurate and robust solutions. This study focuses on the distinct characteristics of tuberculosis lesions, such as their large structures and gradual transitions between healthy and infected tissue. We propose that optimal detection performance may not rely on more complex architectures but instead on optimizing preprocessing techniques to highlight these features. Specifically, a ResNet50-based architecture with Gaussian filtering was evaluated on a dataset of 7,000 images using stratified 5-fold cross-validation. The results show an average accuracy of 99.2%, outperforming the unfiltered model (97.7%) and literature (99.05%), thus setting a new benchmark. The findings demonstrate that leveraging tuberculosis-specific features through Gaussian filtering provides an effective approach to enhance diagnostic performance.
Description
This work is licensed under a Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/).
Version
Published version
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